Survival predictors in patients treated with a molecular adsorbent recirculating system

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Molecular adsorbent recirculating system (MARS).

INTRODUCTION Molecular adsorbent recirculating system (MARS) for albumin liver dialysis has been used as a bridge to liver transplantation in patients with fulminant hepatic failure (FHF). This review examines the available data on its clinical use, its technical aspects and present gaps in knowledge. METHODS Peer-reviewed journals and monographs on the subject were covered. RESULTS FHF is ...

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Thromboelastography to Monitor Clotting/Bleeding Complications in Patients Treated with the Molecular Adsorbent Recirculating System

Background. The Molecular Adsorbent Recirculating System (MARS) has been shown to clear albumin-bound toxins from patients with liver failure but might cause bleeding complications potentially obscuring survival benefits. We hypothesized that monitoring clotting parameters and bed-side thromboelastography allows to reduce bleeding complications. Methods. Retrospective analysis of 25 MARS sessio...

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A case of intractable pruritus in Turner's syndrome successfully treated with molecular adsorbent recirculating system.

Pruritus is the most disabling symptom in patients with cholestatic liver diseases, such as primary biliary cirrhosis, primary sclerosing cholangitis and drug induced cholestasis. Many drug therapies have been used for treating pruritus in these patients, such as histamine antagonists, ursodeoxycholic acid, cholestyramine, enzyme inducing agents as rifampicin or phenobarbital, for inactivation ...

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Meta-analysis of survival with the molecular adsorbent recirculating system for liver failure.

This study aims to assess the treatment effects of the molecular adsorbent recirculating system (MARS) in patients with acute and acute-on-chronic liver failure. We searched MEDLINE, EMBASE, and the Cochrane Controlled Trials Registry database between January 1966 and January 2014. We included randomized controlled trials, which compared the treatment effects of MARS with standard medical treat...

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Extracorporeal membrane oxygenation with multiple-organ failure: Can molecular adsorbent recirculating system therapy improve survival?

BACKGROUND Liver dialysis, molecular adsorbent recirculating system (MARS) particularly, has been used in liver failure to bridge to transplantation. We expanded the indication for MARS to patients with acute shock liver failure and cardiopulmonary failure on extracorporeal membrane oxygenation (ECMO), aiming to improve survival to wean from ECMO. METHODS Retrospective chart analysis of patie...

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ژورنال

عنوان ژورنال: World Journal of Gastroenterology

سال: 2009

ISSN: 1007-9327

DOI: 10.3748/wjg.15.3015